if Windows boots in UEFI mode then the Rescue media must be booted the same, other if Legacy then that mode.

Boot the Rescue Media in the same mode as your Windows OS boots, i.e.

Connect the removed source drive via USB or in a second drive position.

Remove the source drive from your computer and replace it with the new target drive that you want to clone to.

Using a USB stick is the recommended method but do not use a USB stick larger than 32GB in size - an old 1GB stick will do fine! This can be created on DVD or USB stick, plus can be made either with the standard, linux based OS media, or with Windows PE media.

Do not attempt to clone from within Windows! Always use the Acronis bootable Rescue Media to do this.

Please see KB document: 56634: Acronis True Image: Cloning Disks and follow the guide there for cloning your source hard drive - the key points in doing this are as follows: I am sure that lots of users have successfully cloned Windows 10 systems and have seen reports of the same in the forum, though I have not had a need to do so myself.

Windows 10 bootable clone